Some thoughts: I believe that overlap with CV exists and should exist. We are building a community, and I believe we should encourage people put their non-theoretic questions on stats on this site.
I am the author of the first question above and my question was a very real situation I have to deal with in my company. Of course I could ask it in CV, however, I believe that it would be of interest for the members of this site. Probably the same opinion had the at least 5 people that upvoted it, the 2 people that answered it and the 14 people that upvoted their answers (duplicates included).
Similar scenario for question on p-values. The big-data concept and all the implications on statistics are something that statisticians are only very recently start to have to deal with (and history will show how ready they are to change mindsets - so many fields have originated in stats and quickly became independent because classic statisticians were not able to follow or adapt).
Overall I believe we should be open to most statistical questions rather than be ready to declare them off-topic. I prefer to go big and host the union of the different fields/topics that comprise "Data Science" rather than their small intersection.